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U.S. stocks were lower, with the Dow Jones index falling around 550 points on Thursday.

Shares of uniQure N.V. (NASDAQ:QURE) rose sharply during Thursday's session after the company was granted FDA granted Breakthrough Therapy designation for AMT-130 for the treatment of Huntington’s disease.

uniQure shares jumped 45.3% to $13.65 on Thursday.

Here are some other big stocks recording gains in today's session.

• Structure Therapeutics Inc. (NASDAQ:GPCR) gained 21.4% to $22.49.
• Hertz Global Holdings, Inc. (NASDAQ:HTZ) rose 20.3% to $6.99 after Pershing Square Capital Management disclosed a stake via a 13F. CNBC reported that Pershing Square’s stake is 19.8%, through shares & swaps.
• Eli Lilly and Company (NYSE:LLY) gained 15.3% to $847.08 after the company announced topline Phase 3 results from its ACHIEVE-1 trial, which showed orforglipron demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines.
• Capricor Therapeutics, Inc. (NASDAQ:CAPR) rose 13.8% to $10.97.
• ClearPoint Neuro, Inc. (NASDAQ:CLPT) gained 13% to $13.02.
• VersaBank (NASDAQ:VBNK) rose 12% to $10.91.
• Evotec SE (NASDAQ:EVO) jumped 10.7% to $3.6200 following FY24 financial results.
• Avis Budget Group, Inc. (NASDAQ:CAR) gained 10.1% to $80.00. The move came as investors responded to news that billionaire investor Bill Ackman’s Pershing Square Capital Management significantly increased its stake in Hertz Global Holdings Inc (NASDAQ:HTZ).
• Insteel Industries, Inc. (NYSE:IIIN) gained 9.1% to $29.15 following second-quarter results.
• Fidelity National Information Services, Inc. (NYSE:FIS) shares jumped 7% to $73.41. Fidelity National Information Services unveiled two strategic moves—acquiring Global Payments' Issuer Solutions unit and selling its remaining stake in Worldpay.
• Dollar Tree, Inc. (NASDAQ:DLTR) gained 4.4% to $76.40.

Now Read This:

• Intuit To Rally Around 19%? Here Are 10 Top Analyst Forecasts For Thursday

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